Ohio State and ETCR Partner to Advance Research on Drug-Resistant Canine Hookworms

Ohio State’s College of Veterinary Medicine and East Tennessee Clinical Research have signed a licensing agreement to support development of new treatments for drug-resistant canine hookworms.
  • Ohio State and ETCR enter exclusive licensing agreement
  • Focus on multidrug-resistant canine hookworms (Ancylostoma caninum)
  • Enables research, testing, and distribution of resistant parasite strains
  • Supports development of new deworming treatments
  • Addresses growing treatment resistance across North America

The Ohio State University College of Veterinary Medicine and East Tennessee Clinical Research (ETCR) have announced a new licensing agreement aimed at tackling multidrug-resistant canine hookworms, an emerging challenge in companion animal health.

Supporting New Treatment Development

The agreement allows ETCR to use and distribute laboratory-isolated, drug-resistant hookworm larvae for research and testing. These parasites were originally identified and developed by researchers at Ohio State after a clinical case failed to respond to multiple approved deworming treatments.

The goal is to provide a standardized, scientifically validated resource to help animal health companies evaluate new therapies.

Bridging Academic Research and Industry

Under the partnership, Ohio State will continue its work in parasite research, including isolation and characterization, while ETCR will focus on conducting studies and offering commercial research services.

This collaboration creates a pathway for industry partners to test new and existing products against resistant strains in controlled settings.

Growing Concern in Companion Animal Health

Drug-resistant hookworm infections have been increasingly reported in dogs across the United States and Canada, raising concerns within the veterinary community.

The availability of well-characterized resistant strains is expected to accelerate the development of more effective treatments and support regulatory decision-making.

Expanding Access for Research

The agreement also enables controlled access to resistant parasite samples for approved research purposes, helping expand scientific understanding and innovation in parasite control.

By combining academic expertise with industry capabilities, the initiative aims to address a growing gap in effective parasite treatments for dogs.

Information sourced from The Ohio State University College of Veterinary Medicine.